Latest posts
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Oral Semaglutide 25 mg Shows Significant Weight Loss in Adults With Overweight or Obesity
Published in The New England Journal of Medicine (September 17, 2025) Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has already transformed obesity management through its injectable formulation (Wegovy® 2.4 mg) and higher-dose oral option (50 mg). Now, new research highlights the effectiveness of a 25 mg daily oral dose as an alternative for individuals with…
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Non-Surgical Fat Loss Techniques: Current Approaches and Clinical Considerations
Abstract Non-surgical fat loss techniques, also termed non-invasive body contouring modalities, have gained increasing popularity in recent years as alternatives to liposuction and bariatric surgery. These methods target localized adipose deposits through mechanisms such as cryolipolysis, laser therapy, radiofrequency lipolysis, focused ultrasound, and injectable lipolysis. While their efficacy has been demonstrated in selected patient populations,…
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Ecnoglutide Shows Promising Weight Loss Results in New Phase 3 Trial
A next-generation GLP-1 receptor agonist demonstrates significant efficacy and safety for adults with overweight or obesity Introduction: Obesity is a growing global health crisis affecting more than 650 million people worldwide. Beyond aesthetics, it significantly increases the risk of chronic diseases such as type 2 diabetes, cardiovascular disease, certain cancers, and joint problems. While lifestyle…
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Semaglutide in Type 1 Diabetes and Obesity: A Promising New Direction for Dual Disease Management
Keywords: Type 1 diabetes, obesity, semaglutide, GLP-1 receptor agonist, weight loss, glycemic control, insulin therapy Managing both type 1 diabetes (T1D) and obesity remains a significant clinical challenge. While intensive insulin therapy is lifesaving for individuals with T1D, it often contributes to weight gain, further complicating metabolic control and increasing the risk of long-term complications…
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Dual Blockade in Diabetic Kidney Disease: Early Evidence Supports Combined Finerenone and Empagliflozin Therapy
Keywords: Chronic Kidney Disease, Diabetic Nephropathy, Finerenone, Empagliflozin, SGLT2 inhibitors, Mineralocorticoid Receptor Antagonist, CONFIDENCE study The management of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM) remains a growing clinical challenge, with substantial morbidity, mortality, and healthcare costs. While standard therapies—such as renin-angiotensin system (RAS) inhibitors—slow disease progression, residual risk remains…
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Weight Loss Outcomes After GLP-1 Drug Interruptions: Insights from the ENDO 2025 Meeting
A newly presented study at the ENDO 2025 meeting offers clinically significant insights into the impact of GLP-1 receptor agonist interruptions on weight loss outcomes. As global demand for medications such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) continues to rise, many patients face interrupted access due to supply shortages, insurance issues, or cost…
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Can GLP-1 Weight Loss Drugs Like Ozempic Boost Testosterone Levels in Men?
A new study presented at ENDO 2025, the annual meeting of the Endocrine Society, has revealed a surprising benefit of popular weight loss drugs. Besides helping men lose weight and control blood sugar, GLP-1 receptor agonists like Ozempic, Wegovy, Mounjaro, and Trulicity may also help raise testosterone levels naturally. This discovery adds to the growing…
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Managing Diabetes in Overweight and Obese Individuals: The Roles of Semaglutide and Bariatric Surgery
Understanding Diabetes and Its Connection to Obesity Diabetes, particularly type 2 diabetes, has become increasingly prevalent in recent decades, often closely linked with obesity. The physiological interplay between excess weight and insulin resistance is complex and multifaceted, significantly affecting glucose metabolism. In individuals with obesity, increased adiposity, particularly visceral fat, can lead to hormonal changes…
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Understanding Diabesity: Key Concepts and Related Terms
What is Diabesity? Diabesity is defined as the dual condition of obesity coupled with type 2 diabetes. This intersection of metabolic syndrome illustrates the growing obesity epidemic while shedding light on the multifaceted nature of diabetes. The prevalence of diabesity has dramatically increased over recent decades, reflecting not only individual lifestyle choices but also broader…
